In our time, the incidence of vertebral pain syndromes in patients from the USA and Europe varies from 14 to 42%. Additionally, back pain has one of the leading positions as for the reasons for the total complaints. Pain in the lumbosacral area stays one of the most widespread chronic pain symptoms; the incidence of chronic back and neck pain ranges from 24 to 56.7%. Pain in the lower back happens in 8 out of 10 adults, which, along with acute respiratory diseases, represents the main cause of temporary invalidity.
Zanaflex is the medicine that belongs to the group of skeletal muscle relaxants. The main active component of this drug is Tizanidine. The drug is commonly available in the form of 2 or 4 mg pills. The treatment with miorelaxants starts with the therapeutic dose and extends over the entire period of pain retention. Usually, the treatment lasts for a few weeks.
One of the most efficient and safe medications of this class is Sirdalud, whose international generic name is tizanidine. It is known that the painful muscle cramp in combination with the common therapy, miorelaxants, accelerates the pain relief, reduces the muscular tension and increases the mobility of the spine. Clinical researches that compared monotherapy with combination treatment of NSAIDs NSAIDs and tizanidine, have proven the superiority of the latter in effectiveness.
Zanaflex is mainly used for the treatment of the following diseases:
improved muscle tone caused by the back injury
recovery from the spinal operation
As soon as it appears in the patient’s organism, tizanidine arouses some receptors in the spinal cord that block certain amino acids. Consequently, the inhibition of propagation of excitation in the nerve endings lead to the muscular frame back. Thus, the relaxation of the muscles happens, bringing them back to the natural state and relieving pain caused by enhanced tone (restoring the passive and active motion in the spine).
To relieve the muscle cramps, take 2-4 mg of the drug three times a day. In some cases, the dose of 4 mg is required.
In case of spasticity caused by neurological disorders, the dose of drug must be determined individually, depending on the the patient’s reaction to the drug. The starting dose must not exceed 6 mg a day, the frequency of use – 3 times a day.
The dose must be gradually enhanced with an interval of 3-4 to 7 days. The maximum effect is usually achieved at a dose of 12-24 m a day, divided into 3-4 intakes. The highest recommended dose is 36 mg a day.
Patients with kidney dysfunction must take Zanaflex with special caution patients and require the special dosage.
People who feel drowsy during the treatment must avoid any activities that requires high concentration (for example, driving, operating machinery, etc.).
The treatment should be stopped if you have hypersensitivity to the drug ingredients. The safety of Zanaflex during pregnancy and breastfeeding is yet unknown; therefore, you should start the treatment only after the doctor’s approval