Instructions for use indicate that Vardenafil is a selective inhibitor of PDE (phosphodiesterase). Normal erection is controlled by two main processes. The first is the synthesis of cGMP (cyclic guanosine monophosphate), and the second is its disintegration, carried out with the help of PDE.


Description of Vardenafil.

Instructions for use indicate that Vardenafil is a selective inhibitor of PDE (phosphodiesterase). Normal erection is controlled by two main processes. The first is the synthesis of cGMP (cyclic guanosine monophosphate), and the second is its disintegration, carried out with the help of PDE.
Vardenafil blocks phosphodiesterase, thereby increasing the amount of cGMP, and cyclic guanosine monophosphate acts relaxing on the smooth muscle fibers of the cavernous bodies of the penis, increasing the flow of blood to them. This process causes an erection.

Vardenafil has analogues and generics. Popular counterparts:
Viagra (sildenafil).
Cialis (tadalafil).
The most famous generic drug is Levitra.

The purpose of Vardenafil.

Instructions for use of Vardenafil contain information that the remedy is recommended for an insufficient genital reaction (code F52.2 on the international classification of diseases). Under this convoluted formulation, many diseases are concealed, the leading symptoms of which are:
Inability to achieve or maintain an erection and fully complete the sexual act.
Complete absence of an erection on the background of various diseases that are not directly related to the reproductive system.

As Vardenafil (or generic Levitra), so sildenafil and tadalafil do not cure completely of impotence. These drugs can eliminate the symptoms of ailment for a while, that is, if necessary, contribute to the emergence of a full erection. However, the cause of erectile dysfunction of phosphodiesterase inhibitors do not eliminate. Comments of doctors practicing the prescription of medicine confirm it.
The instructions for use clearly state the contraindications to the prescription of the drug Vardenafil.
Diseases of the heart and blood vessels. This includes various diseases in which physical (including sexual) stress poses a threat to the life and health of a man:

Recent myocardial infarction.
Chronic heart failure.
Stenocardia of tension (and other forms of unstable angina pectoris).

Vardenafil or its generic can’t be taken together with nitrates (oxygen donors) and inhibitors of CYP3A4, which is associated with the specific metabolism of vardenafil in the body. Admission is prohibited with erythromycin, rotone viro, clarithromycin, intraconazole, etc.

Contraindication is an allergy to any component of the drug or its individual intolerance.
The patient is under 18 years old. Clinical trials in this age group have not been conducted.
Also in the instruction special situations are listed, where the appointment in theory is possible, but potentially unsafe for health.
Serious violations of hepatic function with hepatic insufficiency.

A marked decrease in blood pressure (hypotension) to the numbers 90/55 mm Hg. Art.
Vardenafil and its generic can be recommended with great caution to representatives of the stronger sex with congenital or acquired deformity of the penis, who have diseases with a high risk of priapism (myeloma, sickle-cell anemia, leukemia), peptic ulcer of the stomach and duodenum.
Renal failure (terminal stage with the use of hemodialysis).

There is no evidence of the effects of Vardenafil administration on men with retinitis pigmentosa.
The presented list of contraindications is incomplete and is of a fact-finding nature. More detailed information is printed in the annotation. Even if you have not found any of the aforementioned ailments, the use of the medicine without prior consultation with a doctor is prohibited. Comments of doctors indicate a high risk of complications with misappropriation of funds.

Vardenafil, like any PDE inhibitor, can have an adverse effect on the body. The frequency of development of certain side effects is prescribed in the instructions:
You can buy Vardenafil on our website in any quantity.

Heart and blood vessels: heartbeat, rapid heart rate, hypotension are rarely observed. In post-marketing observations of Vardenafil application, cases of myocardial infarction in patients taking Vardenafil or generic were documented. However, it was not possible to reliably determine the true cause of the development of pathology, because many men had a large number of concomitant diseases (diabetes, coronary heart disease, hypertension).

Respiratory system: congestion of the nose and paranasal sinuses.

Gastrointestinal tract: a frequent occurrence was dyspepsia. Less frequently nausea, diarrhea, gastralgia, gastritis are observed.

Organs of the senses: conjunctivitis, achromatopsia (violation of the normal perception of color) were witnessed from the side of sight. Very rarely there was an increase in intraocular pressure. From the side of the organ of hearing, there was a ringing in the ears.

Nervous system: all PDE inhibitors (including sildenafil and tadalafil) often cause a headache. This is a leading side effect of Vardenafil, noted in about 10% of patients, which is confirmed by the researchers. Also, some of them were worried about dizziness, fainting, cramps, paresthesia. However, their frequency was much lower.

Immune system: allergic reactions of varying severity.
Genitourinary system: priapism (a long and painful erection).


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