Composition, description and form of Straterra. In what form is the drug Straterra sold? Consumer testimonials say that this remedy can be found in pharmacies in the form of capsules of different colors, which depends on the mass content of the active ingredient. The medicament in question includes an active substance such as atomoxetine in the form of a hydrochloride. It also contains additional components in the form of dimethicone, pregelatinized starch, titanium dioxide, gelatin, dyes and sodium lauryl sulfate.
Pharmacology of Straterra
Do you know what the “Straterra” capsules are? The doctors’ comments indicate that this medication belongs to the group of sympathomimetics, which have a central effect and possess such a highly selective potent active component as atomoxetine. By the way, the latter is an inhibitor of transports (presynaptic) norepinephrine. The drug under consideration has a slight affinity for other receptors of the noradrenergic system or neurotransmitter transporters. The drug “Straterra”, the reviews from which are indicated below, is not a psychoactive stimulant, nor does it apply to amphetamine derivatives. In the process of clinical trials, withdrawal of treatment with this medication did not lead to negative symptoms or increased manifestations of the disease.
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Pharmacokinetics of Straterra medication.
How does the absorption of the drug “Straterra” occur? The reviews report that, when taken orally, the active element of this drug is quickly and practically completely absorbed from the digestive tract. The greatest plasma concentration of atomoxetine in the blood is observed after 60-110 minutes.
The distribution of this drug in the human body is quite extensive. It binds well to plasma proteins, especially albumin. Metabolism of atomoxetine (primary) is carried out in the liver via the isoenzyme CYP2D6. When oral capsules are taken, the average half-life time of atomoxetine in people with fast metabolism is 3.5 hours, and in patients with delayed – 21 hours. The main way to remove this medication is the kidney system. The pharmacokinetics of the drug in childhood from 6 years is similar to the pharmacokinetics of adults.
Indications of Straterra
In what cases is the drug “Straterra” most effective? Reviews of adults tell us that this medication is ideal for patients aged 6 years with attention deficit hyper-responsiveness syndrome. Prohibitions to use. Are there any contraindications to the medicine “Straterra”? (For children this medicine should be prescribed only by an experienced doctor) Doctors state that the following conditions for an absolute prohibition to taking this drug are: glaucoma is closed in coal; severe heart failure; hypersensitivity to atomoxetine and other elements of the drug; age up to 6 years; parallel treatment with MAO inhibitors.
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The specific purpose of the drug Straterra
The drug “Straterra”, reviews about which are more positive, is prescribed with caution in: arterial hypertension; joint therapy with psychostimulants; tachycardia; cardiovascular diseases; work associated with heavy physical load; sudden heart fatal death in anamnesis, convulsive seizures; disorders of the blood circulation of the brain. Capsules “Straterra” (medicine): the instruction of experts indicates that the drug in question is intended only for oral administration, once a day.
Treatment with this drug should be done only under the supervision of a doctor who specializes in the therapy of people with ADHD. When observing negative effects in the case of a single daily intake of capsules, the dosage should be divided into 2 divided doses (preferably every 12 hours). The abolition of this remedy almost never leads to negative symptoms, so treatment does not require a phased reduction in doses.
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The average recommended dosage of this drug per day for children weighing up to 70 kg is 500 mkg / kg. Later this amount should be increased to therapeutic, which is 1.2 mg / kg (not earlier than 3 days). In the absence of the proper therapeutic effect, an increase in the dose to 1.8 mg / kg is possible, but not earlier than 15-30 days after the initiation of therapy. The average recommended dosage for children weighing 70 kg, as well as adults, is 40 mg. Subsequently, this amount is raised to a therapeutic dose, which is 80 mg, but not earlier than 3 days later. In the absence of a therapeutic effect, the dose of the drug is increased to 120 mg (approximately after 2-4 weeks). In the presence of pathology of the hepatic of a moderate nature, the standard amount of the medicinal product is reduced by half, and in severe cases – by a factor of four. What are the adverse reactions caused by the drug “Straterra”?Parents’ comments. Parents of children aged 6 years who used this medication for ADHD therapy say that against the background of his admission, their babies often had abdominal pain and decreased appetite. Usually such symptoms were temporary and did not require the abolition of therapy.