The name “Viagra” is known to almost any adult, but not many people know that this drug acts due to the active ingredient sildenafil included in its composition. It helps to cope with the manifestations of erectile dysfunction and other problems of male potency. Found by us about the preparation sildenafil citrate reviews unequivocally testify that to this day it remains the most popular and effective medicine for the treatment of potency disorders in the stronger sex. Sildenafil citrate really helps! You can buy sildenafil citrate on our website.
Sildenafil citrate in any remedy for impotence, regardless of the brand name under which it is manufactured, has one principle of action. The active component is an inhibitor of a special substance – phosphodiesterase (PDE). The normal process of sexual arousal in a stronger sex is always accompanied by the synthesis of a large number of cyclic guanosine monophosphate (cGMP), which has a relaxing effect on the musculature of the penis. In turn, this increases the blood flow in the penis and strengthens the erection, which is necessary in some forms of impotence.
PDE destroys guanosine monophosphate and blocks increased blood flow. Sildenafil citrate, by destroying phosphodiesterase, on the contrary, will increase cGMP and thus have a therapeutic effect.
Instructions for the use of any generic (Sildenafil vertex, Maxigra) and the very original of Viagra will contain identical indications for the use of the drug. It is recommended to take the remedy if there are:
Erectile dysfunction, which arose against the background of a preserved libido.
Insufficient (slow) erection.
Inability to complete sexual contact due to problems with erection.
Sildenafil citrate does not treat impotence, and this should be taken into account when appointing. The drug solves physiological problems without affecting the etiology (cause) of the development of impotence. Therefore it is better to combine: simultaneously prescribe Sildenafil tablets and etiologic treatment. In addition, the manufacturer indicates the need for sexual stimulation to achieve a full effect. The erection itself can’t come.
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There are no standard appointments for Sildenafil. Depending on the presence of concomitant pathology, individual characteristics of the male body, the dosage regimen may change. It is impossible to focus on the reviews of people who have already taken the medicine. The only correct dosage will be chosen by the doctor. An indicative scheme, which is of a fact-finding nature, is presented below.
In some situations, the dosage is increased to 100 mg. The standard method of taking is the ingestion of Sildenafil tablets at the prescribed dosage 1 hour before the alleged sexual coition. Separately, we should focus on whether alcohol and Sildenafil are compatible. This we will discuss below.
When is it strictly prohibited?
Instructions for the use of any drug that contains a PDE inhibitor, whether Sildenafil-SZ or an analogue of Vertex, indicates that you can’t always consume them. Categorical contraindications to the appointment of an inhibitor of PDE are:
Diseases in which a man receives nitrate therapy.
The patient is under 18 years old.
Intolerance to milk sugar or a violation of the normal mechanism of its malabsorption if it is included in the drug as an inactive ingredient.
In addition, it is forbidden to take tablets with sildenafil in the presence of hypersensitivity to any component of the drug. Clinical trials have not been conducted on the combined effect of several generics containing a PDE inhibitor on the body, so combining them is not recommended.
Also, manufacturers point out that in some situations, taking medicine with sildenafil should be under the supervision of a doctor.
This will be a group of conditional contraindications:
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Exacerbation of gastric ulcer and duodenal ulcer.
Leukemia, myeloma, thrombocythemia and other diseases that increase the risk of pianism (a painful erection lasting about 6 hours).
Genetically determined pigmentosa retinitis. The manufacturer of the original Sildenafil (Viagra) reports that clinical trials involving men suffering from this ailment have not been carried out.
Recent acute pathology of the cardiovascular system. Patients of this group are very vulnerable, so excessive sexual activity can become a real threat to their life and health for them.
Pronounced hypotension. The PDE inhibitor operates mainly selectively, so for healthy representatives of the stronger sex, its vasodilating effect will be imperceptible. However, for hypotension, the use of sildenafil increases the risk of complications.
Congenital or acquired anatomical features of the structure of the penis (for example, Peyronie’s disease) can be a serious obstacle to the normal operation of sildenafil.
A separate point is the fact that taking an inhibitor of PDE is inappropriate for women (including pregnant and lactating). The proper effect of taking Sildenafil will not be achieved, but the side effect can manifest. Also, the manufacturer points in the annotation to the fact that sildenafil citrate in the body can interact with certain drugs, so there are limitations in its joint appointment. For more information, consult your doctor or read the summary.