Salbutamol is widely used to stop or prevent the asthmatic attacks and bronchospasm. Acting on the adrenergic receptors of the bronchi and blood vessels, this tool is able to increase lung capacity and reduce the resistance in the airways, and thus prevent a bronchospasm. Doctors also note that this drug reduces the tone of the myometrium and expands the coronary arteries. You will find more information about Proventil in this article.
Proventil is available in aerosol form for inhalation. Active substance of the drug is salbutamol sulfate, which contains 1 dose of 124 mg. Auxiliary substances of this product are ethanol and hydrofluroalkane. The drug is released in an aluminum container, which is provided with a dispenser. A single pressing gives 1 dose containing 0.1 mg of the drug. Proventil is available in the form tablets and solution for intravenous injection.
This drug assists in the expectoration, prevents the occurrence of bronchospasm of allergic origin, has an impact on the breakdown of glycogen and the production of insulin, and reduces the concentration of potassium in the blood. At the same time, according to experts, Proventil does not increase blood pressure, and has no negative impact on the heart and blood vessels. At the same time, the coronary vessels of the heart may slightly expand under the influence of the drug. The therapeutic effect occurs immediately after administration of Proventil, literally within 2-4 minutes and continues for three hours or more. This drug in tablet form acts longer, up to 7-8 hours, however, the therapeutic effect does not occur earlier than after 30 minutes.
Indications for the use of the drug are to prevent and stop asthma attacks. In addition, this tool has proved to be excellent in the treatment of chronic bronchitis, emphysema, airway obstruction, and also in combating child broncho-obstructive syndrome. The drug is used obstetrics and in obstetric practice, for example, it assigns the risk of preterm birth, which is caused by strong uterine activity.
Proventil in the form of aerosol is used in cases when it is necessary to stop an asthma attack. Adults are recommended to have 1-2 injections at one time, whereas children can have only 1 dose. Adults should have 2 doses of injection 3-4 times a day in order to prevent asthma attacks, and children – one dose of the same 3-4 times a day. If an asthma attack occurs during exercise, you should inject Proventil for half an hour to children and adults at 1 and 2 doses, respectively.
The instruction mentions the following side effects that can be caused by the drug: nausea, headache, vomiting, dizziness, mild tachycardia, hypotension, collapse, and urticaria. In addition, it is necessary to monitor the level of potassium in the body to prevent the appearance of hypokalemia.
Considering contraindications of Proventil, you must say that this medication is not prescribed in the first and second trimester of pregnancy, and to patients with threatened miscarriage. It should not be used by individuals with allergy to salbutamol sulfate and other components of the medication, as well as children up to two years. The drug should be used with caution by diabetics, individuals with glaucoma, myocarditis, and acute heart failure.