Which group do lithium preparations belong to?
Lithium is a part of the group of normotimics – these are drugs whose clinical effectiveness consists in balancing and stabilizing mood disorders. They are used in pharmacology for the treatment of depressive states, manic and affective disorders. Lithium preparations are normotimics and are able to remove symptoms of irritability and impulsiveness, smooth out the instability of character. Medicines have a psychotropic effect. Thanks to their use, doctors have prevented more than one suicide. Normotimics also constructively struggle with chronic addictions and sexual deviations, treat borderline and reactive personality disorders. Previously, lithium was used as anti-epileptic drugs, now they are replaced by antidepressants (from depression) and neuroleptics (from mania). Normotimics have a complex effect when the patient changes from depressive to manic and vice versa (manic-depressive psychosis). You can buy the drug from our website.
The main pharmacological action of lithium is the activation of reuptake by adrenergic endings in the central nervous system of free nor-epinephrine and serotonin, which form the development of affective states. The therapeutic effect reduces the number of β-adrenergic receptors and suppresses nor-adrenergic activity. Lithium ions oppress sodium ions in nerve and muscle cells, thereby interfering with the transport of monovalent cations through membranes and weakening nerve impulses. “Li” blocks the activity of enzymes of neuronal dehydrogenases synthesizing inositol, which regulates the sensitivity and cellular respiration of neurons. Medical therapy “Li” shows the best results in the treatment of mixed affect, when patients have the presence of manic syndrome. At the same time, between the phases of the cycle there should be a sufficiently large bright gap, then lithium exhibits a stabilizing effect on the patient’s psyche. Lithium can be purchased from our website at affordable prices.
Classification of drugs: what are used and what are not.
Only some lithium preparations are used in pharmacology: Lithium carbonate (Mikalit, Kamkolit, Contemnol, Litarex, Sedalit, Priadel, Litosan-SR, Quilonum retard, Lithium-durulose, Litionite-dyurel) is most often used and shows a pronounced normotimic effect. Lithium oxybutyrate (oxybate) is an oxybutyric acid salt used in lower concentrations and has less pronounced side effects but has a high activity. Nicotinate (Litonite) is a nicotinic acid salt that improves metabolism. Therefore, it is prescribed as an auxiliary component in the treatment of chronic alcoholism. It is produced in ampoules for injection. Sodium oxy butyrate (GHB) is an oxalic sodium salt, similar to sedative properties with lithium oxybate, but is more often used intravenously or intramuscularly for general anesthesia. Non-anional anesthesia has a mild antihypoxic effect and can be used in surgery for children and the elderly (the drug is well tolerated). In neurology it is assigned to relieve nervous states, repay the state of shock, normalize sleep (for narcolepsy is used as an anti-doping).
For non-medical purposes it is used in dietary supplements for bodybuilders, as an activator of muscle building and a stimulator of growth hormone. Such lithium salts are: citrate, sulfate, chloride, orotate. These drugs have the same properties as carbonate, but are prohibited for use. Earlier, citrate (a compound with citric acid) was part of the beverage “Seven Up” as an anti-hangover component. Scope and purposes. Indications for the use of basic lithium preparations: Lithium carbonate has a prolonged effect and is widely used in the psychiatric industry for such diagnoses as: manic phase and prevention of exacerbations of bipolar affective disorder, iso-effective disorders, chronic alcoholism, certain forms of drug dependence, sexual abnormalities, migraine, Meniere’s syndrome. The practice of therapy of lithium carbonate with progressive muscular dystrophy is known. Also, the drug is used for the therapy of various neuromuscular diseases (including Duchenne myostrophy and spinal amyotrophy) – the clinical picture after the therapeutic course was marked by the increase in muscle strength and increased motor activity. Lithium oxybatyr (Lithii oxybutyras) has a pronounced effect with the same clinical conditions as with the administration of carbonate. Oxy-butyrate lithium and sodium are similar in properties and treat recurrent nervous disorders with manic attacks. The lithium hydroxybutyric acid salt is administered intramuscularly and has less toxicity. Lithium nicotinate (Lithium nicotinate) reduces the craving for alcohol and is prescribed for the treatment of chronic alcoholism, acute intoxication, withdrawal syndrome. The therapeutic effect is expressed against the background of the formation of alcoholic motivation, and against the background of the already emerging alcohol dependence. Lithium succinate is used for external use in skin dermatitis, seborrhea and fungal diseases.